Pierre Fabre (PR - Pharma)
Single Hurricane® Cyclone for Active Pharmaceutical Ingredient recovery after a 12.5m3/h at 25ºC flow rate.
This equipment is composed by 1 hurricane cyclone ø70mm
MVD: 275 µm
Efficiency: 99.95%
Pierre Fabre
France
2011
Hovione, Loures (PR - Pharma)

Single Hurricane® cyclone for Pharmaceutical Powder Recovery after a 1,500kg/h N2 + 40kg/h H2O at 85ºC spray dryer. 

It was installed to replace an existing high efficiency cyclone from the spray dryer manufacturer in order to increase powder recovery.
Median Volume Diameter (MVD): 5.5 µm
Efficiency: > 97% 

Hovione
Loures, Portugal
2008
Hovione New Jersey (PR - Pharma)

Single Hurricane® cyclone for pharmaceutical powder recovery after a 82kg/h N2 at 70ºC spray dryer.  


  • It was installed to replace an existing high efficiency cyclone from the spray dryer manufacturer in order to increase powder recovery 
  • Emissions: N/A
Hovione
New Jersey, USA
2010
Merck (PR - Pharma)

Single Hurricane® cyclone optimized for API recovery after a mixer with 3,400m3/h flow rate at 75ºC.

The cyclone is ø 800 mm, manufactured in AISI 316L under the most strict pharmaceutical quality standards.
Expected efficiency: 98.6-98.8 %

Confidential
France
2012
Hovione New Jersey 2 (Pharma)

Single Hurricane cyclone for pharmaceutical powder recovery after a 112kg/h N2 at 89ºC spray dryer.

The system is composed by 1 hurricane cyclone with ø130mm
MVD: 1.6 µm
Efficiency: > 80%
Hovione
USA
2010
Pulmatrix (PR-Pharma)

Single Hurricane cyclone for pharmaceutical powder recovery after a 112kg/h N2 at 60-100ºC spray dryer. 

  • The system is composed by 1 hurricane cyclone with ø125mm 
  • Emissions: N/A
Pulmatrix
USA
2010
Confidential (PR - Pharma)

Hurricane system designed for product recovery on a nitrogen gas stream of 113 m3/h flow rate at -85 ºC.

  • The system is composed by 2 hurricane cyclones with ø105mm. 
  • Efficiency: > 99.98%
IPSEN
France
2011
TEVA (PR - Pharma)

Single Hurricane cyclone to increase powder recovery after spray dryer processing a 74m3/h gas flow rate at 40ºC.

  • MVD: 6 µm with a pressure drop of 140 mm w. g.
  • Emissions: 95%
TEVA
India
2012
Confidential 04 (PR - Pharma) - merck

Single Hurricane cyclone optimized for API recovery after a mixer with 3 400m3/h flow rate at 75ºC.

  • The cyclone is ø 800 mm, manufactured in AISI 316L under the most strict pharmaceutical quality standards. 
  • Expected efficiency: 98.6 - 98.8%
Merck
France
2012
Confidencial 03 (PR - Pharma) - Ipsen

Hurricane system designed for product recovery on a nitrogen gas stream of 113 m3/h flow rate at -85 ºC.

  • The system is composed by 2 Hurricane cyclones with ø105 mm.
  • Efficiency: > 99.98%
IPSEN
France
2012
HR (Spray Dryer) API
Hurricane HR Cyclone System to increase the yield of powder captured after a pharmaceutical spray-dryer at Hovione (1450 Kg/h N2 at 85ºC)
  • Inlet particulate load (Kg/h) [5-6]
  • Predicted efficiency (%) [>97%]
Hovione
Portugal
2012
Hurricane HR Cyclone system to capture pharmaceutical waste particles from the combined flow of a deduster and a tablet press machine for product waste compliance at Actavis/Teva (416m3/h at 20º).
Hurricane HR Cyclone system to capture pharmaceutical waste particles from the combined flow of a deduster and a tablet press machine for product waste compliance at Actavis/Teva (416m3/h at 20º).
Expected pressure drop (kPa) [1.8]
Expected removal efficiency (%) [98.3-98.6]
Actavis / Teva Pharmaceuticals
USA
2017
Hurricane
Numerically optimized cyclones, considering particle agglomeration

Hurricane geometries maximize powder collection for each different application, while minimizing reentrainment and keeping pressure drop at reasonable levels.


These high efficiency cyclones are the output of nonconvex nonlinear problems formulated and solved after years of work in partnership with the Faculty of Engineering of Porto.


A single Hurricane is more efficient than any other known cyclone available in the market for the same pressure drop, usually resulting in less than half of the emissions of other high efficiency cyclones available.

Very high efficiencies: under 20 % of the emissions of other high efficiency cyclones.
Custom geometry for each case (single or parallel arrangement)
Low pressure drop: < 100 mm w. g.
Direct product discharge avoiding product degradation and cross contamination
Flanged connection for easier installation
Inspection doors for cleaning
"2B" smooth surface finishing when needed
Materials of construction in Carbon Steel or Stainless Steel 304L or 316L
Absence of condensation with heat tracing systems
Clean in Place (CIP) cleaning systems
Very low maintenance and downtime costs

1. Air and Dust from Dryer or Boiler
2. Hurricane Cyclone
3. Valve
4. Collected Particles
5. Clean Air

Efficient recovery of active pharmaceutical ingredients (APIs), chemical substances or food powders after drying applications such as spray and fluid bed drying is frequently a problem. The same problem occurs in many milling and micronization applications.


The preferred way to recover these sensitive and expensive products is with cyclone collectors due to their direct powder capture. Unlike bag filters or wet scrubbers, cyclones minimize filter or product contamination and product cross contamination and can easily handle a wide range of operating temperature, pressure and moisture conditions.


Product losses due to cyclones low efficiency represents a high cost of lower yields. And therefore, when necessary, cyclones have to be complemented with expensive specialized bag filters or wet scrubbers to increase yield or to avoid emissions to the atmosphere.


Client's needs include a cyclone system that dramatically increases powder yield, is easy and fast to clean and is efficient enough to comply with regulatory PM limits, thus avoiding the use of a bag filter. In several processes the fraction of product escaping to the bag filter is not considered as first grade product, and therefore considered a loss.

Pharmaceutical Ingredients
Pharmaceutical Ingredients
Pharmaceutical Ingredients
Pharmaceutical Ingredients

Spray Drying | General Arrangement


Usual spray drying arrangements (single point, two point and closed cycle) include a high efficiency cyclone and a bag filter.


The cyclone serves the purpose of separating and collecting the dried powder originated in the spray drying chamber. In pharmaceutical/API powders, the fraction of product escaping to the bag filter is not considered as first grade product, and thus seen as losses. The main reasons for this are contamination with filter fibers, product cross contamination and risk of heat degradation.


For fine powders with a median diameter in volume (MVD) of less than 5 µm, losses due to low cyclone efficiency can rise to more than 25 %.

Fluid Bed Drying | General Arrangement


In fluidized bed arrangements, cyclones are used to recover the fine fraction of the dried powder, collecting or returning it to the bed. This fraction frequently has a very small particle size distribution, which results in low yields in the cyclone. Improving the efficiency is crucial both to recover first grade product and to reduce filter bag cleaning and frequent change of bags.


Client needs include a cyclone system efficient enough in order to replace the bag filter and comply with regulatory emission limits.